Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | MIF | P14174 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049673 | 0.85 | MAPK1 (0.72) | ALDH1A1NPSR1MAPK1TSHRHPGD | |
| SCHEMBL2149867 | 0.82 | ALDH1A1 (0.72) | ALDH1A1NPSR1MAPK1TSHRHPGD | |
| SCHEMBL9210565 | 0.82 | ALDH1A1 (0.72) | ALDH1A1NPSR1MAPK1TSHRHPGD | |
| SCHEMBL5539569 | 0.82 | ALDH1A1 (0.72) | ALDH1A1NPSR1MAPK1TSHRHPGD | |
| SCHEMBL31236314 | 0.82 | ALDH1A1 (0.72) | ALDH1A1NPSR1MAPK1TSHRHPGD | |
| SCHEMBL6639178 | 0.82 | ALDH1A1 (0.72) | ALDH1A1NPSR1MAPK1TSHRHPGD | |
| SCHEMBL30416948 | 0.82 | ALDH1A1 (0.72) | ALDH1A1NPSR1MAPK1TSHRHPGD | |
| SCHEMBL2008321 | 0.81 | MAPK1 (0.75) | ALDH1A1NPSR1MAPK1TSHRHPGD | |
| Benzene SCHEMBL7861838 | 0.81 | MAPK1 (0.75) | ALDH1A1NPSR1MAPK1TSHRHPGD | |
| Hydrochloric Acid SCHEMBL28948388 | 0.81 | ALDH1A1 (0.70) | ALDH1A1NPSR1MAPK1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705832-B1 | Serotonergic modulators | LILLY CO ELI (GB) | 2003-08-13 | — | — | EP | disclosed |
| US-5817822-A | ANTITUOR, ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | NOVARTIS CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5563147-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0705832-A1 | Serotonergic modulators | LILLY INDUSTRIES LIMITED (GB) | 1996-04-10 | — | — | EP | disclosed |
| EP-0555251-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007838-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | disclosed |
| US-4227915-A | N-Substituted oxobenzothiazoline and oxobenzoxazoline derivatives and their use as plant growth regulants | MONSANTO COMPANY (US) | 1980-10-14 | — | — | US | disclosed |