Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 17/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.53 |
| ▸ | PDE4A | P27815 | 16/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.53 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020123 | 0.91 | PDE4D (0.51) | PDE4DPDE4BPDE4APDE4CGCK | |
| SCHEMBL7017344 | 0.86 | PDE4A (0.52) | PDE4DPDE4BPDE4APDE4CGCK | |
| SCHEMBL7015704 | 0.80 | PDE4D (0.59) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7021594 | 0.79 | PDE4D (0.59) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7020796 | 0.78 | PDE4B (0.50) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7011316 | 0.74 | PDE4D (0.64) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7020524 | 0.71 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7019218 | 0.70 | PDE4B (0.49) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7019051 | 0.70 | PDE4B (0.47) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6943421 | 0.69 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086106-B1 | FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE | DARWIN DISCOVERY LTD (GB) | 2003-08-20 | — | — | EP | claimed |