Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 20/20 | 0.59 |
| ▸ | PDE4A | P27815 | 18/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021594 | 0.84 | PDE4D (0.59) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7020796 | 0.84 | PDE4B (0.50) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7011973 | 0.81 | PDE4A (0.49) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7017103 | 0.80 | PDE4D (0.53) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7019218 | 0.75 | PDE4B (0.49) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7016224 | 0.75 | PDE4A (0.39) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8333880 | 0.74 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7016598 | 0.74 | PDE4A (0.67) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7019362 | 0.73 | PDE4A (0.48) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7017332 | 0.73 | PDE4A (0.51) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086106-B1 | FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE | DARWIN DISCOVERY LTD (GB) | 2003-08-20 | — | — | EP | claimed |