Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.67 |
| ▸ | CTSV | O60911 | 4/20 | 0.67 |
| ▸ | CTSL | P07711 | 3/20 | 0.67 |
| ▸ | CTSK | P43235 | 11/20 | 0.64 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804155 | 0.95 | CTSS (0.73) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL5253507 | 0.91 | CTSK (0.76) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL6799742 | 0.91 | CTSS (0.63) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL4457833 | 0.90 | CTSK (0.65) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL13677172 | 0.90 | CTSK (0.79) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL4449512 | 0.89 | CTSK (0.67) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL6807956 | 0.89 | CTSK (0.81) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL4457932 | 0.89 | CTSK (0.58) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL4444451 | 0.89 | CTSS (0.58) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL4459411 | 0.88 | CTSK (0.68) | CTSSCTSVCTSLCTSKCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362052-A1 | INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES | Amura Therapeutics Limited (GB) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002057270-A1 | INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES | AMURA THERAPEUTICS LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |