Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014979 | 0.81 | AGTR2 (0.52) | AGTR2AGTR1 | |
| SCHEMBL7014033 | 0.78 | AGTR2 (0.72) | AGTR2AGTR1 | |
| SCHEMBL7011288 | 0.78 | AGTR2 (0.58) | AGTR2AGTR1 | |
| SCHEMBL7017061 | 0.78 | AGTR2 (0.58) | AGTR2AGTR1 | |
| SCHEMBL8911666 | 0.77 | AGTR2 (0.49) | AGTR2AGTR1 | |
| SCHEMBL9085616 | 0.76 | AGTR2 (0.56) | AGTR2AGTR1 | |
| SCHEMBL8910295 | 0.76 | AGTR1 (0.58) | AGTR2AGTR1 | |
| SCHEMBL7145725 | 0.76 | AGTR2 (0.57) | AGTR2AGTR1 | |
| SCHEMBL7016557 | 0.76 | PPARG (0.58) | AGTR2AGTR1 | |
| SCHEMBL7015279 | 0.76 | AGTR2 (0.57) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520423-B1 | Heterocyclic compounds, their production and use as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6100252-A | SPECIFIED COMPOUNDS INCLUDING METHYL 2-BUTYL-1-((2'-(2-OXO-3H-1,2,3,5-OXATHIADIAZOL-4-YL)BIPHENYL) METHYL)-BENZIMIDAZOLE-7-CARBOXYLATE; USE TO TREAT CIRCULATORY DISEASES SUCH AS HYPERTENSIVE DISEASES AND HEART DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0520423-A2 | Heterocyclic compounds, their production and use as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-30 | — | — | EP | disclosed |