Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10511469 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SOAT1NPC1MAPK1MAPT | |
| SCHEMBL9461194 | 0.72 | JMJD6 (0.44) | ALDH1A1JMJD6NPC1MAPK1RAB9A | |
| SCHEMBL3258080 | 0.70 | ADORA3 (0.40) | ALDH1A1JMJD6SOAT1NPC1RAB9A | |
| SCHEMBL28570578 | 0.70 | ALDH1A1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL6677747 | 0.69 | ALDH1A1 (0.41) | ALDH1A1SOAT1MAPK1RAB9AMAPT | |
| SCHEMBL10871776 | 0.69 | ALDH1A1 (0.38) | ALDH1A1SOAT1ADORA3ADORA2AADORA1 | |
| SCHEMBL7014619 | 0.68 | EDNRB (0.42) | ALDH1A1SOAT1ADORA3ADORA2AMAPT | |
| SCHEMBL1758561 | 0.68 | ALDH1A1 (0.36) | ALDH1A1SOAT1NPC1RAB9ALMNA | |
| SCHEMBL5983543 | 0.68 | ADORA2A (0.38) | ALDH1A1JMJD6SOAT1NPC1RAB9A | |
| SCHEMBL4664835 | 0.68 | ADORA2A (0.44) | ALDH1A1SOAT1NPC1RAB9AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353640-B2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| EP-0353640-B1 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0353640-A2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | Hoechst Schering AgrEvo GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |