Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25216516 | 0.84 | PDE10A (0.51) | RAB9ANPC1PDE10AMEN1KMT2A | |
| SCHEMBL8825750 | 0.82 | RAB9A (0.57) | RAB9ANPC1PDE10AHSD17B10MEN1 | |
| SCHEMBL7849624 | 0.81 | PDE10A (0.64) | RAB9ANPC1PDE10AHSD17B10MEN1 | |
| SCHEMBL7014997 | 0.80 | RAB9A (0.55) | RAB9ANPC1PDE10AHSD17B10MEN1 | |
| SCHEMBL9832053 | 0.77 | RAB9A (1.00) | RAB9ANPC1PDE10AHSD17B10MEN1 | |
| SCHEMBL259906 | 0.77 | PDE10A (0.64) | RAB9ANPC1PDE10AJAK2JAK3 | |
| SCHEMBL7013765 | 0.76 | RAB9A (0.57) | RAB9ANPC1HSD17B10MEN1KMT2A | |
| SCHEMBL7016465 | 0.76 | RAB9A (0.57) | RAB9ANPC1PDE10AHSD17B10MEN1 | |
| SCHEMBL258891 | 0.75 | PDE10A (1.00) | PDE10A | |
| SCHEMBL23572047 | 0.74 | PDE10A (0.48) | RAB9ANPC1PDE10AHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972774-B1 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-a)pyridines | DOW AGROSCIENCES LLC (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-0717743-B1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0972774-A3 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5571775-A | EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES | DOWELANCO (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996001826-A1 | N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-01-25 | — | — | WO | disclosed |