Sugi Predict

Sugi Predict / Compounds / SCHEMBL7013765

SCHEMBL7013765

SCHEMBL7013765

Nc1cccn2nc(SCc3ccccc3)nc12

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 6/20 0.57
▸ NPC1 O15118 5/20 0.57
▸ SMN1; SMN2 Q16637 3/20 0.49
▸ POLB P06746 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ ALOX15 P16050 2/20 0.46
▸ HSP90AA1 P07900 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ HDAC1 Q13547 7/20 0.43
▸ METAP2 P50579 1/20 0.43
▸ HPGD P15428 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ KDM1A O60341 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7016465 0.83 RAB9A (0.57) RAB9ANPC1SMN1; SMN2POLBHSD17B10
SCHEMBL8825756 0.82 RAB9A (0.59) RAB9ANPC1SMN1; SMN2HSD17B10ALOX15
SCHEMBL7014552 0.78 RAB9A (0.51) RAB9ANPC1POLBHSD17B10MEN1
SCHEMBL7018170 0.76 RAB9A (0.62) RAB9ANPC1SMN1; SMN2HSD17B10ALOX15
SCHEMBL7840644 0.75 RAB9A (0.50) RAB9ANPC1SMN1; SMN2POLBHSD17B10
SCHEMBL7014524 0.75 RAB9A (0.47) RAB9ANPC1SMN1; SMN2POLBHSD17B10
SCHEMBL8825876 0.75 RAB9A (0.58) RAB9ANPC1SMN1; SMN2POLBHSD17B10
SCHEMBL9832053 0.72 RAB9A (1.00) RAB9ANPC1SMN1; SMN2HSD17B10ALOX15
SCHEMBL10557053 0.72 SMN1; SMN2 (0.53) RAB9ANPC1SMN1; SMN2POLBHSD17B10
SCHEMBL7017512 0.70 ALDH1A1 (0.46) RAB9ANPC1SMN1; SMN2POLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0972774-B1 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-a)pyridines DOW AGROSCIENCES LLC (US) 2003-02-26 — — EP disclosed
EP-0972774-B1 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-a)pyridines DOW AGROSCIENCES LLC (US) 2003-02-26 — — EP disclosed
EP-0717743-B1 N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES DOW AGROSCIENCES LLC (US) 2001-11-14 — — EP disclosed
EP-0972774-A3 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines Dow AgroSciences LLC (US) 2001-10-31 — — EP disclosed
EP-0972774-A3 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines Dow AgroSciences LLC (US) 2001-10-31 — — EP disclosed
EP-0972774-A2 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines Dow AgroSciences LLC (US) 2000-01-19 — — EP disclosed
EP-0972774-A2 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines Dow AgroSciences LLC (US) 2000-01-19 — — EP disclosed
EP-0972774-A2 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines Dow AgroSciences LLC (US) 2000-01-19 — — EP disclosed
EP-0789698-B1 N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES DOW AGROSCIENCES LLC (US) 1999-07-07 — — EP disclosed
US-5763359-A N-(1-ethyl-4-pyrazolyl)triazoloazinesulfonamide herbicides DOW AGROSCIENCES LLC (US) 1998-06-09 — — US disclosed
EP-0789698-A1 N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES DOWELANCO (US) 1997-08-20 — — EP disclosed
WO-1997008172-A1 N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES DOWELANCO (US) 1997-03-06 — — WO disclosed
US-5571775-A EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES DOWELANCO (US) 1996-11-05 — — US disclosed
EP-0717743-A1 N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES DOWELANCO (US) 1996-06-26 — — EP disclosed
WO-1996001826-A1 N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES DOWELANCO (US) 1996-01-25 — — WO disclosed