Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144327 | 0.86 | LMNA (0.42) | LMNAHSD17B10KDM4ECASP1NPC1 | |
| SCHEMBL27869365 | 0.80 | MAPT (0.40) | LMNAHSD17B10KDM4ECASP1NPC1 | |
| SCHEMBL8324045 | 0.79 | TSHR (0.42) | LMNAHSD17B10KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL9069781 | 0.79 | LMNA (0.48) | LMNAHSD17B10KDM4ECASP1NPC1 | |
| SCHEMBL27989024 | 0.78 | CA12 (0.39) | LMNAHSD17B10KDM4ECASP1NPC1 | |
| SCHEMBL28794544 | 0.78 | GBA1 (0.44) | LMNAKDM4ENPC1KMT2ASMN1; SMN2 | |
| SCHEMBL27852492 | 0.78 | CYP1A2 (0.38) | LMNAHSD17B10KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL16415718 | 0.78 | LMNA (0.47) | LMNAHSD17B10KDM4ECASP1NPC1 | |
| Propane SCHEMBL11522719 | 0.78 | TSHR (0.51) | LMNAHSD17B10NPC1KMT2AMEN1 | |
| SCHEMBL27869394 | 0.77 | ALDH1A1 (0.39) | LMNAHSD17B10KDM4ECASP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003667-A | TYK-2 inhibitors | 百济神州有限公司 | 2022-09-02 | — | — | CN | disclosed |
| EP-0972774-B1 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-a)pyridines | DOW AGROSCIENCES LLC (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-0717743-B1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5700940-A | FOR PRE- OR POSTEMERGENCE SPRAYING OF PLANTS OR SOILS | DOWELANCO (US) | 1997-12-23 | — | — | US | disclosed |
| US-5571775-A | EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES | DOWELANCO (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0717743-A1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1996001826-A1 | N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-01-25 | — | — | WO | disclosed |