Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884662 | 0.84 | HTR6 (0.52) | KDM4EALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL29506329 | 0.74 | HSD11B1 (0.91) | KDM4EHSD11B1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL3486583 | 0.74 | HSD11B1 (0.91) | KDM4EHSD11B1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL3146296 | 0.72 | KDM4E (0.58) | KDM4EHSD11B1ALDH1A1LMNAFFAR4 | |
| SCHEMBL3925050 | 0.72 | HSD11B1 (0.67) | KDM4EHSD11B1ALDH1A1LMNACA12 | |
| SCHEMBL3006653 | 0.72 | HSD11B1 (0.67) | KDM4EHSD11B1ALDH1A1LMNACA12 | |
| SCHEMBL12336997 | 0.71 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL30939460 | 0.71 | SMN1; SMN2 (0.57) | KDM4EHSD11B1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29227967 | 0.71 | SMN1; SMN2 (0.57) | KDM4EHSD11B1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3485583 | 0.71 | KDM4E (1.00) | KDM4EHSD11B1ALDH1A1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877022-B1 | Sulfonylpyrimidine derivatives with anticancer activity | RUDJER BOSKOVIC INST (HR) | 2003-04-16 | — | — | EP | disclosed |