Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 11/20 | 0.49 |
| ▸ | NPY1R | P25929 | 12/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016743 | 0.91 | KCNH2 (0.48) | KCNH2NPY1RPRKDCBRD4AKT1 | |
| SCHEMBL7015058 | 0.89 | KCNH2 (0.47) | KCNH2NPY1RPRKDCBRD4AKT1 | |
| SCHEMBL7015665 | 0.88 | KCNH2 (0.48) | KCNH2NPY1RPRKDCBRD4AKT1 | |
| SCHEMBL7016153 | 0.87 | KCNH2 (0.48) | KCNH2NPY1RPRKDCBRD4EGFR | |
| SCHEMBL12946506 | 0.87 | KCNH2 (0.48) | KCNH2NPY1RPRKDCBRD4EGFR | |
| SCHEMBL7015881 | 0.83 | KCNH2 (0.51) | KCNH2NPY1RPRKDCBRD4KDM4E | |
| SCHEMBL7015353 | 0.81 | KCNH2 (0.56) | KCNH2NPY1RPRKDCBRD4 | |
| SCHEMBL960822 | 0.81 | KCNH2 (0.77) | KCNH2NPY1RPRKDCBRD4 | |
| SCHEMBL7019934 | 0.80 | NPY1R (0.61) | KCNH2NPY1R | |
| SCHEMBL113716 | 0.79 | KCNH2 (0.41) | KCNH2NPY1RPRKDCBRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |