Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967607 | 0.81 | — | — | |
| SCHEMBL7014735 | 0.76 | MAPT (0.44) | — | |
| SCHEMBL14991484 | 0.75 | ALDH1A1 (0.41) | TSHR | |
| SCHEMBL15837553 | 0.73 | TDP1 (0.45) | TSHR | |
| SCHEMBL4444114 | 0.73 | TSHR (0.33) | TSHR | |
| SCHEMBL4444111 | 0.73 | TSHR (0.33) | TSHR | |
| SCHEMBL16480677 | 0.73 | ALOX15 (0.36) | TSHR | |
| SCHEMBL6783950 | 0.73 | TDP1 (0.45) | TSHR | |
| SCHEMBL6719953 | 0.73 | TSHR (0.33) | TSHR | |
| SCHEMBL7019426 | 0.72 | TSHR (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |