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SCHEMBL7018767

SCHEMBL7018767

CC(NC(=O)C(NS(=O)(=O)c1ccc(F)cc1)c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GFER P55789 1/20 0.57
▸ NPC1 O15118 1/20 0.53
▸ POLB P06746 1/20 0.51
▸ ALDH1A1 P00352 4/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ MMP1 P03956 1/20 0.49
▸ MMP2 P08253 1/20 0.49
▸ MMP3 P08254 1/20 0.49
▸ MMP7 P09237 1/20 0.49
▸ MMP9 P14780 1/20 0.49
▸ MMP13 P45452 1/20 0.49
▸ HPN P05981 2/20 0.47
▸ PLAU P00749 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026805 0.91 GFER (0.60) GFERPOLBALDH1A1MEN1KMT2A
SCHEMBL7022882 0.88 HPN (0.60) GFERPOLBALDH1A1MEN1KMT2A
SCHEMBL7020606 0.87 GFER (0.57) GFERPOLBALDH1A1MEN1KMT2A
SCHEMBL7026718 0.87 BMP1 (0.57) GFERPOLBALDH1A1CYP3A4CYP2D6
SCHEMBL7024095 0.85 KDM4E (0.61) GFERPOLBALDH1A1MEN1KMT2A
SCHEMBL7025505 0.84 GFER (0.54) GFERPOLBALDH1A1MEN1KMT2A
SCHEMBL27504621 0.84 GFER (0.54) GFERPOLBALDH1A1MEN1KMT2A
SCHEMBL2013525 0.82 SLC1A3 (0.56) MEN1KMT2AMMP1MMP2MMP3
SCHEMBL7023550 0.79 MEN1 (0.54) GFERPOLBALDH1A1MEN1KMT2A
SCHEMBL29223118 0.74 CNR1 (0.58) POLBALDH1A1MMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1071660-B1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE SYNGENTA PARTICIPATIONS AG (CH) 2003-01-22 — — EP claimed
US-6391918-B1 FUNGICIDES SYNGENTA CROP PROTECTION, INC. 2002-05-21 — — US claimed
CN-1291973-A N-sulphonyl and N-sulphinyl phenylglycinamide NOVARTIS AG (CH) 2001-04-18 — — CN claimed
EP-1071660-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE Novartis AG (CH) 2001-01-31 — — EP claimed
WO-1999043644-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE___________________ NOVARTIS AG (CH) 1999-09-02 — — WO claimed
CN-1226284-C N-sulphonyl and N-sulphinyl phenylglycinamide SYNGENTA PARTICIPATIONS AG (CH) 2005-11-09 — — CN disclosed
CN-1226284-C N-sulphonyl and N-sulphinyl phenylglycinamide SYNGENTA PARTICIPATIONS AG (CH) 2005-11-09 — — CN disclosed
EP-1071660-B1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE SYNGENTA PARTICIPATIONS AG (CH) 2003-01-22 — — EP disclosed
EP-1071660-B1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE SYNGENTA PARTICIPATIONS AG (CH) 2003-01-22 — — EP disclosed
US-6391918-B1 FUNGICIDES SYNGENTA CROP PROTECTION, INC. 2002-05-21 — — US disclosed
US-6391918-B1 FUNGICIDES SYNGENTA CROP PROTECTION, INC. 2002-05-21 — — US disclosed
CN-1291973-A N-sulphonyl and N-sulphinyl phenylglycinamide NOVARTIS AG (CH) 2001-04-18 — — CN disclosed
CN-1291973-A N-sulphonyl and N-sulphinyl phenylglycinamide NOVARTIS AG (CH) 2001-04-18 — — CN disclosed
EP-1071660-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE Novartis AG (CH) 2001-01-31 — — EP disclosed
EP-1071660-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE Novartis AG (CH) 2001-01-31 — — EP disclosed
WO-1999043644-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE___________________ NOVARTIS AG (CH) 1999-09-02 — — WO disclosed
WO-1999043644-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE___________________ NOVARTIS AG (CH) 1999-09-02 — — WO disclosed