SCHEMBL7022882

SCHEMBL7022882

Cc1ccc(S(=O)(=O)NC(C(=O)NC(C)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPN P05981 2/20 0.60
PLAU P00749 1/20 0.60
KCNA5 P22460 1/20 0.58
GFER P55789 1/20 0.58
ALDH1A1 P00352 6/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
POLB P06746 1/20 0.52
GAA P10253 2/20 0.49
NPSR1 Q6W5P4 1/20 0.48
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP3 P08254 1/20 0.48
MMP7 P09237 1/20 0.48
MMP9 P14780 1/20 0.48
MMP13 P45452 1/20 0.48
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026805 0.92 GFER (0.60) HPNPLAUKCNA5GFERALDH1A1
SCHEMBL7020606 0.88 GFER (0.57) HPNPLAUKCNA5GFERALDH1A1
SCHEMBL7018767 0.88 GFER (0.57) HPNPLAUGFERALDH1A1MEN1
SCHEMBL7026718 0.88 BMP1 (0.57) HPNPLAUGFERALDH1A1POLB
SCHEMBL7024095 0.86 KDM4E (0.61) GFERALDH1A1MEN1KMT2APOLB
SCHEMBL27504621 0.85 GFER (0.54) HPNPLAUGFERALDH1A1MEN1
SCHEMBL7025505 0.85 GFER (0.54) GFERALDH1A1MEN1KMT2APOLB
SCHEMBL1000596 0.83 ALDH1A1 (0.62) HPNPLAUALDH1A1MEN1KMT2A
SCHEMBL2161085 0.83 ALDH1A1 (0.62) HPNPLAUALDH1A1MEN1KMT2A
SCHEMBL2161104 0.83 ALDH1A1 (0.62) HPNPLAUALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1071660-B1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE SYNGENTA PARTICIPATIONS AG (CH) 2003-01-22 EP claimed
US-6391918-B1 FUNGICIDES SYNGENTA CROP PROTECTION, INC. 2002-05-21 US claimed
EP-1071660-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE Novartis AG (CH) 2001-01-31 EP claimed
WO-1999043644-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE___________________ NOVARTIS AG (CH) 1999-09-02 WO claimed
CN-1226284-C N-sulphonyl and N-sulphinyl phenylglycinamide SYNGENTA PARTICIPATIONS AG (CH) 2005-11-09 CN disclosed
EP-1071660-B1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE SYNGENTA PARTICIPATIONS AG (CH) 2003-01-22 EP disclosed
EP-1071660-B1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE SYNGENTA PARTICIPATIONS AG (CH) 2003-01-22 EP disclosed
US-6391918-B1 FUNGICIDES SYNGENTA CROP PROTECTION, INC. 2002-05-21 US disclosed
US-6391918-B1 FUNGICIDES SYNGENTA CROP PROTECTION, INC. 2002-05-21 US disclosed
CN-1291973-A N-sulphonyl and N-sulphinyl phenylglycinamide NOVARTIS AG (CH) 2001-04-18 CN disclosed
EP-1071660-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE Novartis AG (CH) 2001-01-31 EP disclosed
EP-1071660-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE Novartis AG (CH) 2001-01-31 EP disclosed
WO-1999043644-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE___________________ NOVARTIS AG (CH) 1999-09-02 WO disclosed
WO-1999043644-A1 N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE___________________ NOVARTIS AG (CH) 1999-09-02 WO disclosed