SCHEMBL7018792

SCHEMBL7018792

CCOP(=O)(OCC)Oc1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.60
CA1 P00915 2/20 0.60
BCHE P06276 1/20 0.60
ACHE P22303 1/20 0.60
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
LTA4H P09960 1/20 0.46
TSHR P16473 2/20 0.45
CYP3A4 P08684 1/20 0.45
BLM P54132 1/20 0.44
CA12 O43570 1/20 0.44
ESR1 P03372 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
ESR2 Q92731 1/20 0.44
CA14 Q9ULX7 1/20 0.44
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20582588 0.96 CA1 (0.56) CA2CA1BCHEACHEMEN1
SCHEMBL5026807 0.90 CA2 (0.70) CA2CA1BCHEACHEMEN1
SCHEMBL11547365 0.89 GAA (0.54) CA2CA1BCHEACHEMEN1
SCHEMBL11544837 0.85 GAA (0.54) CA2CA1BCHEACHEMEN1
SCHEMBL20710745 0.82 CA1 (0.62) CA2CA1BCHEACHEMEN1
SCHEMBL3294100 0.82 TSHR (0.69) CA2CA1BCHEACHEMEN1
SCHEMBL25299492 0.81 TSHR (0.48) CA2CA1BCHEACHEMEN1
SCHEMBL22322000 0.81 CA2 (0.57) CA2CA1BCHEACHEMEN1
SCHEMBL906952 0.81 CA2 (0.57) CA2CA1BCHEACHEMEN1
SCHEMBL556916 0.81 CA1 (0.57) CA2CA1BCHEACHEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117050259-A Silicon-phosphorus block intrinsic flame-retardant polyurea material and preparation method thereof 北京化工大学 2023-11-14 CN claimed
CN-118240396-A Reinforced fiber for composite floor and preparation method thereof 广西大自然智能家居有限公司 2024-06-25 CN disclosed
CN-117050259-A Silicon-phosphorus block intrinsic flame-retardant polyurea material and preparation method thereof 北京化工大学 2023-11-14 CN disclosed
CN-108342058-B The master batch of VOCs in recycled polyester can be removed under illumination and no light condition 东华大学 2019-07-12 CN disclosed
CN-108396404-B Low VOC type Regenerated Polyester Fibres and preparation method thereof 优彩环保资源科技股份有限公司 2019-06-11 CN disclosed
US-20080319209-A1 Process for Preparing (Disubstitutedpropenyl) Phenylalkyl Substituted Dihydrobenzofurans BAYER CROPSCIENCE AG (DE) 2008-12-25 US disclosed
US-20080319209-A1 Process for Preparing (Disubstitutedpropenyl) Phenylalkyl Substituted Dihydrobenzofurans BAYER CROPSCIENCE AG (DE) 2008-12-25 US disclosed
WO-2007005450-A2 IMPROVED PROCESS FOR PREPARING (DISUBSTITUTEDPROPENYL) PHENYLALKYL SUBSTITUTED HETEROCYCLES BAYER CROPSCIENCE AG (DE) 2007-01-11 WO disclosed
EP-0574174-B1 Angiotensin II antagonists LILLY CO ELI (US) 2003-08-13 EP disclosed
US-6090889-A FATTY ALCOHOL OR ETHYLENE VINYL ACETATE ARE GRAFTED ONTO AN ACRYLIC POLYMER THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-07-18 US disclosed
US-5693633-A Angiotensin II antagonists ELI LILLY AND COMPANY (US) 1997-12-02 US disclosed
US-5612360-A AROMATIC N-HETEROCYCLIC COMPOUNDS AS HYPOTENSIVE AGENTS WITH ACID GROUPS, SULFONYLCARBOXAMIDES OR TETRAZOLE GROUPS ELI LILLY AND COMPANY (US) 1997-03-18 US disclosed
US-5569768-A USEFUL IN TREATING HYPERTENSION, CONGESTIVE HEART FAILURE, GLAUCOMA AND RENAL INSUFFICIENCY ELI LILLY AND COMPANY (US) 1996-10-29 US disclosed
US-5556981-A Angiotensin II antagonist intermediates ELI LILLY AND COMPANY (US) 1996-09-17 US disclosed
US-5484780-A CARDIOVASCULAR, HYPOTENSIVE ELI LILLY AND COMPANY (US) 1996-01-16 US disclosed
CN-1101908-A Angiotensin II antagonists LILLY CO ELI (US) 1995-04-26 CN disclosed
US-5401851-A Preparation of proline derivatives ELI LILLY AND COMPANY (US) 1995-03-28 US disclosed
CN-1085897-A Angiotension II antagonists LILLY CO ELI (US) 1994-04-27 CN disclosed
EP-0574174-A2 Angiotensin II antagonists ELI LILLY AND COMPANY (US) 1993-12-15 EP disclosed
EP-0573271-A1 Angiotensin II antagonists ELI LILLY AND COMPANY (US) 1993-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319209-A1 Process for Preparing (Disubstitutedpropenyl) Phenylalkyl Substituted Dihydrobenzofurans CYP2F1, CYP4X1, C1S CA2 4687/4885CA1 4822/4885BCHE 2776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.