SCHEMBL11544837

SCHEMBL11544837

CCOP(=O)(Oc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1)Oc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.54
PKM P14618 3/20 0.54
CA2 P00918 3/20 0.50
CA1 P00915 2/20 0.50
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50
ELANE P08246 2/20 0.48
CA12 O43570 1/20 0.44
CA4 P22748 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43
KMT2A Q03164 3/20 0.41
POLB P06746 2/20 0.40
MAPT P10636 1/20 0.40
ESR1 P03372 1/20 0.40
ALDH1A1 P00352 2/20 0.38
ENPP2 Q13822 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11547365 0.97 GAA (0.54) GAAPKMCA2CA1BCHE
SCHEMBL20582588 0.89 CA1 (0.56) GAACA2CA1BCHEACHE
SCHEMBL11546324 0.87 GAA (0.50) GAAPKMELANELTA4H
SCHEMBL7018792 0.85 CA2 (0.60) GAACA2CA1BCHEACHE
SCHEMBL11542640 0.84 GAA (0.50) GAAPKMELANEESR1LTA4H
SCHEMBL11543065 0.83 PKM (0.64) GAAPKMCA2CA1ELANE
SCHEMBL11552735 0.83 PKM (0.64) GAAPKMCA2CA1ELANE
SCHEMBL11544891 0.81 CYP3A4 (0.61) GAAPKMACHEELANEKMT2A
SCHEMBL11546278 0.80 GAA (0.54) GAAPKMCA2CA1ELANE
SCHEMBL5880409 0.80 GAA (0.50) GAAPKMCA2CA1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4168365-A Flame-retardant phenolic resin MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1979-09-18 US claimed
US-4168365-A Flame-retardant phenolic resin MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1979-09-18 US disclosed