Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019214 | 0.87 | LTB4R (0.43) | LTB4R | |
| SCHEMBL7019517 | 0.84 | LMNA (0.37) | SLC6A2SLC6A4SLC6A3LTB4R | |
| SCHEMBL8862053 | 0.75 | LTB4R (0.53) | LTB4R | |
| SCHEMBL8862049 | 0.75 | LTB4R (0.53) | LTB4R | |
| SCHEMBL7018870 | 0.75 | LTB4R (0.53) | PAMLTB4R | |
| SCHEMBL7021927 | 0.70 | LTB4R (0.66) | LTB4R | |
| SCHEMBL9491471 | 0.70 | LTB4R (0.47) | LTB4R | |
| SCHEMBL8080183 | 0.69 | LTB4R (0.48) | CXCL8LTB4R | |
| SCHEMBL8080568 | 0.69 | LTB4R (0.44) | CXCL8LTB4R | |
| SCHEMBL7022628 | 0.68 | LTB4R (0.60) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649412-B1 | PHARMACEUTICAL PYRIDINE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2003-01-15 | — | — | EP | disclosed |
| US-5990314-A | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-23 | — | — | US | disclosed |
| US-5643914-A | Pharmaceutical pyridine compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0733044-A4 | COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0733044-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0649412-A4 | PHARMACEUTICAL PYRIDINE COMPOUNDS. | SMITHKLINE BEECHAM CORP (US) | 1995-07-05 | — | — | EP | disclosed |
| WO-1995015950-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |
| EP-0649412-A1 | PHARMACEUTICAL PYRIDINE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994000437-A1 | PHARMACEUTICAL PYRIDINE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | disclosed |