Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015241 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL5635440 | 0.77 | LMNA (0.39) | LMNABLMALDH1A1 | |
| SCHEMBL17369606 | 0.74 | LMNA (0.41) | LMNABLMALDH1A1 | |
| SCHEMBL1513027 | 0.72 | — | — | |
| SCHEMBL329051 | 0.72 | LMNA (0.39) | LMNABLMALDH1A1 | |
| SCHEMBL15353077 | 0.71 | LMNA (0.35) | LMNABLMALDH1A1 | |
| SCHEMBL224000 | 0.70 | LMNA (0.38) | LMNABLMALDH1A1 | |
| SCHEMBL3067524 | 0.70 | LMNA (0.38) | LMNABLMALDH1A1 | |
| SCHEMBL15293795 | 0.70 | LMNA (0.43) | LMNABLMALDH1A1 | |
| SCHEMBL13784413 | 0.70 | LMNA (0.38) | LMNABLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |