Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024618 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7017123 | 0.90 | ALDH1A1 (0.56) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7017004 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7015989 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7021365 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7017362 | 0.82 | PTGER2 (0.43) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7026869 | 0.82 | PTGER2 (0.43) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL29640604 | 0.80 | ALDH1A1 (0.64) | ALDH1A1PTGER3PTGER4PTGIRPPARG | |
| SCHEMBL7022721 | 0.79 | PDE4D (0.34) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7030341 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789022-B1 | Difluoroprostacyclins, intermediates for production thereof and processes for production thereof | ASAHI GLASS CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| EP-0669329-B1 | Difluorprostacyclins, intermediates for production thereof and processes for production thereof | ASAHI GLASS CO LTD (JP) | 1998-05-20 | — | — | EP | disclosed |
| EP-0789022-A1 | Difluoroprostacyclins, intermediates for production thereof and process for production | ASAHI GLASS COMPANY LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5616732-A | Intermediates for difluoroprostacyclins and methods for their production | ASAHI GLASS COMPANY LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5538995-A | Difluoroprostacyclins | ASAHI GLASS COMPANY LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0669329-A1 | Difluorprostacyclins, intermediates for production thereof and processes for production thereof | ASAHI GLASS COMPANY LTD. (JP) | 1995-08-30 | — | — | EP | disclosed |