SCHEMBL29640604

SCHEMBL29640604

CCCCC[C@H](O)/C=C/[C@@H]1[C@@H]2[C@H](C[C@H]1O)O/C(=C\CCCC(=O)O)C2(F)F

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
PPARG P37231 1/20 0.60
PPARD Q03181 1/20 0.60
PPARA Q07869 1/20 0.60
PTGER4 P35408 5/20 0.54
TBXA2R P21731 5/20 0.54
PTGER1 P34995 3/20 0.54
PTGER3 P43115 3/20 0.54
LMNA P02545 3/20 0.54
PTGFR P43088 2/20 0.54
PTGDR Q13258 1/20 0.54
SLCO2A1 Q92959 1/20 0.54
PTGER2 P43116 4/20 0.49
PTGIR P43119 3/20 0.49
HPGD P15428 3/20 0.49
TSHR P16473 3/20 0.49
MAPK1 P28482 2/20 0.49
NR1I2 O75469 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7030341 0.91 ALDH1A1 (0.53) ALDH1A1MEN1KMT2APPARGPPARD
SCHEMBL7017123 0.90 ALDH1A1 (0.56) ALDH1A1MEN1KMT2APPARGPPARD
SCHEMBL8566554 0.83 ALDH1A1 (0.44) ALDH1A1MEN1KMT2APPARGPPARD
SCHEMBL7021427 0.82 PTGER2 (0.53) ALDH1A1MEN1KMT2APPARGPPARD
SCHEMBL22687373 0.82 PTGER2 (0.53) ALDH1A1MEN1KMT2APPARGPPARD
SCHEMBL7015989 0.81 ALDH1A1 (0.42) ALDH1A1MEN1KMT2APPARGPPARD
SCHEMBL7017004 0.81 ALDH1A1 (0.42) ALDH1A1MEN1KMT2APPARGPPARD
SCHEMBL7024618 0.80 ALDH1A1 (0.45) ALDH1A1MEN1KMT2APPARGPPARD
SCHEMBL7018997 0.80 ALDH1A1 (0.45) ALDH1A1MEN1KMT2APPARGPPARD
SCHEMBL8567060 0.80 PTGER4 (0.41) ALDH1A1MEN1KMT2APPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250205518-A1 PULMONARY HYPERTENSION TREATMENT SONIVIE LTD. (IL) 2025-06-26 US disclosed
US-12251582-B2 Pulmonary hypertension treatment SONIVIE LTD. (IL) 2025-03-18 US disclosed
US-20220241617-A1 PULMONARY HYPERTENSION TREATMENT SONIVIE LTD. (IL) 2022-08-04 US disclosed
US-11318331-B2 Pulmonary hypertension treatment SONIVIE LTD. (IL) 2022-05-03 US disclosed