Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28073064 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL8889910 | 0.94 | PDE4A (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL27277190 | 0.94 | PDE4A (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL23698704 | 0.86 | LMNA (0.33) | LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL8575383 | 0.79 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL14411838 | 0.79 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL10614196 | 0.76 | PDE4A (0.44) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL6038229 | 0.75 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL9707240 | 0.75 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL18210863 | 0.75 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165564-A4 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | IND RES LTD (NZ) | 2003-01-22 | — | — | EP | disclosed |
| EP-1165564-A2 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | INDUSTRIAL RESEARCH LIMITED (NZ) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000061783-A2 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | INDUSTRIAL RESEARCH LIMITED (NZ) | 2000-10-19 | — | — | WO | disclosed |