Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956419 | 0.77 | SLC6A2 (0.52) | SLC6A2SLC6A4L3MBTL1LMNAALDH1A1 | |
| SCHEMBL4616539 | 0.76 | SLC6A2 (0.51) | SLC6A2SLC6A4L3MBTL1LMNAALDH1A1 | |
| SCHEMBL4614754 | 0.74 | SLC6A2 (0.50) | SLC6A2SLC6A4L3MBTL1LMNAALDH1A1 | |
| SCHEMBL11070894 | 0.72 | SLC6A2 (0.48) | SLC6A2SLC6A4L3MBTL1LMNAALDH1A1 | |
| SCHEMBL10664881 | 0.71 | SLC6A2 (0.50) | SLC6A2SLC6A4L3MBTL1LMNAALDH1A1 | |
| SCHEMBL11740967 | 0.70 | SLC6A2 (0.46) | SLC6A2SLC6A4L3MBTL1LMNAALDH1A1 | |
| SCHEMBL11739205 | 0.69 | SLC6A2 (0.48) | SLC6A2SLC6A4L3MBTL1LMNAALDH1A1 | |
| SCHEMBL11741513 | 0.69 | TDP1 (0.50) | SLC6A2SLC6A4L3MBTL1LMNAALDH1A1 | |
| SCHEMBL11741262 | 0.67 | TDP1 (0.51) | SLC6A2SLC6A4L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7019186 | 0.67 | RAB9A (0.62) | L3MBTL1LMNAALDH1A1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705832-B1 | Serotonergic modulators | LILLY CO ELI (GB) | 2003-08-13 | — | — | EP | disclosed |
| US-5563147-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0705832-A1 | Serotonergic modulators | LILLY INDUSTRIES LIMITED (GB) | 1996-04-10 | — | — | EP | disclosed |