Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30194878 | 0.82 | SMN1; SMN2 (0.70) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL10652650 | 0.77 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL4615852 | 0.77 | L3MBTL1 (0.64) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11443619 | 0.76 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11709456 | 0.75 | MEN1 (0.50) | ALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL11349942 | 0.75 | L3MBTL1 (0.66) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL4617266 | 0.74 | CYP3A4 (0.64) | RAB9ANPC1SMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL11436081 | 0.74 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL4614755 | 0.73 | L3MBTL1 (0.69) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL2149244 | 0.73 | L3MBTL1 (0.65) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705832-B1 | Serotonergic modulators | LILLY CO ELI (GB) | 2003-08-13 | — | — | EP | disclosed |
| US-5563147-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0705832-A1 | Serotonergic modulators | LILLY INDUSTRIES LIMITED (GB) | 1996-04-10 | — | — | EP | disclosed |