Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019084 | 0.91 | MAOA (0.46) | CASRCTNNB1TCF7L2LMNAMAPT | |
| SCHEMBL7015657 | 0.81 | TP53 (0.52) | LMNAMAPTSMN1; SMN2MAOBPOLB | |
| SCHEMBL7017431 | 0.76 | MEN1 (0.52) | LMNAMAPTSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL7011070 | 0.76 | MEN1 (0.52) | LMNAMAPTSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL7008944 | 0.75 | CASR (0.45) | CASRSMN1; SMN2RAB9A | |
| SCHEMBL7011506 | 0.75 | MEN1 (0.55) | MAPTSMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL7021766 | 0.75 | MEN1 (0.46) | SMN1; SMN2L3MBTL1RAB9AHTTALDH1A1 | |
| SCHEMBL7015787 | 0.74 | MEN1 (0.51) | CASRLMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL7017988 | 0.73 | MEN1 (0.61) | LMNATSHRPOLBL3MBTL1RAB9A | |
| SCHEMBL7101327 | 0.72 | MEN1 (0.60) | LMNAMAPTSMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-5753664-A | ANTITUMOR AGENTS, PYRIMIDONES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |