Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019348 | 1.00 | F2 (0.45) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7017847 | 0.83 | F2 (0.49) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7026202 | 0.80 | F2 (0.49) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7019033 | 0.79 | TPSAB1 (0.47) | F2PRSS1 | |
| SCHEMBL7019035 | 0.79 | TPSAB1 (0.47) | F2PRSS1 | |
| SCHEMBL3238624 | 0.76 | F2 (0.70) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8186956 | 0.75 | F2 (0.57) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7019470 | 0.74 | MAPT (0.54) | — | |
| SCHEMBL7019474 | 0.74 | MAPT (0.54) | — | |
| SCHEMBL7025245 | 0.74 | F2 (0.55) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |