Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RNF4 | P78317 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025481 | 0.83 | NPY5R (0.39) | NPY5RHDAC1KMT2AMEN1GAA | |
| SCHEMBL7896868 | 0.80 | NPY5R (0.50) | NPY5RHDAC1KMT2AMEN1GAA | |
| SCHEMBL7898569 | 0.77 | NPY5R (0.47) | NPY5RHDAC1KMT2AMEN1GAA | |
| SCHEMBL7895718 | 0.73 | HPGD (0.47) | HDAC1KMT2AMEN1GAAPOLB | |
| SCHEMBL7019453 | 0.69 | RAB9A (0.77) | KMT2AMEN1GAAPOLBSMN1; SMN2 | |
| SCHEMBL10789758 | 0.68 | CXCR4 (0.44) | HDAC1GAASMN1; SMN2LMNATP53 | |
| SCHEMBL10789750 | 0.68 | CXCR4 (0.44) | HDAC1GAASMN1; SMN2LMNATP53 | |
| SCHEMBL21316586 | 0.67 | HPGD (0.66) | HDAC1RECQLRNF4SMN1; SMN2LMNA | |
| SCHEMBL23573012 | 0.67 | FFAR1 (0.61) | FFAR1FFAR4 | |
| SCHEMBL12167954 | 0.67 | RAB9A (0.77) | HDAC1KMT2AMEN1GAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973735-B1 | POLYAROMATIC ANTIVIRAL COMPOSITIONS | UPJOHN CO (US) | 2003-01-29 | — | — | EP | claimed |
| US-5958983-A | NOVEL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST HERPES, TOPICAL ADMINISTRATION THEM TO TREAT PATIENTS WITH HERPES; WORK BY INHIBITING THE INITIATION OF HERPES VIRAL DNA SYNTHESIS IN HOST CELLS | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-28 | — | — | US | claimed |
| EP-0973735-B1 | POLYAROMATIC ANTIVIRAL COMPOSITIONS | UPJOHN CO (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1148048-A2 | Polyaromatic antiviral compositions | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-24 | — | — | EP | disclosed |
| US-6147116-A | TOPICALLY ADMINISTERING BENZENE DERIVATIVE SUBSTITUTED WITH UREIDO-, THIOUREIDO, AND/OR SULFONAMIDO GROUPS TO TREAT HERPES | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-14 | — | — | US | disclosed |
| US-5958983-A | NOVEL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST HERPES, TOPICAL ADMINISTRATION THEM TO TREAT PATIENTS WITH HERPES; WORK BY INHIBITING THE INITIATION OF HERPES VIRAL DNA SYNTHESIS IN HOST CELLS | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-28 | — | — | US | disclosed |