Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.55 |
| ▸ | F7 | P08709 | 11/20 | 0.47 |
| ▸ | F3 | P13726 | 11/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017912 | 0.88 | F2 (0.69) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7023800 | 0.80 | F2 (0.62) | F2F7F3PRSS1PRSS2 | |
| SCHEMBL7311846 | 0.79 | F2 (0.44) | F2PRSS1PRSS2PRSS3TRPA1 | |
| SCHEMBL7019819 | 0.76 | F2 (0.53) | F2PRSS1PRSS2PRSS3TRPA1 | |
| SCHEMBL7022614 | 0.74 | F2 (0.56) | F2PRSS1PRSS2PRSS3TRPA1 | |
| SCHEMBL7022618 | 0.74 | F2 (0.56) | F2PRSS1PRSS2PRSS3TRPA1 | |
| SCHEMBL7028108 | 0.74 | F2 (0.56) | F2PRSS1PRSS2PRSS3TRPA1 | |
| SCHEMBL7317972 | 0.74 | F2 (0.71) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7671130 | 0.74 | F2 (0.71) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7677981 | 0.71 | F2 (0.48) | F2PRSS1PRSS2PRSS3TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | claimed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | claimed |
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |