Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018463 | 0.89 | NPY1R (0.43) | NPY1RKCNH2TSHRLMNAKMT2A | |
| SCHEMBL7012960 | 0.80 | NPY1R (0.46) | NPY1RKCNH2MAPT | |
| SCHEMBL7012855 | 0.78 | NPY1R (0.56) | NPY1RKCNH2 | |
| SCHEMBL7012282 | 0.76 | HTR2C (0.38) | NPY1RTSHRLMNAPOLBKMT2A | |
| SCHEMBL7015448 | 0.75 | NPY1R (0.49) | NPY1RKCNH2TSHRPIK3C2B | |
| SCHEMBL12946434 | 0.75 | NPY1R (0.51) | NPY1RKCNH2 | |
| SCHEMBL7019032 | 0.75 | NPY1R (0.55) | NPY1RKCNH2 | |
| SCHEMBL7010773 | 0.74 | NPY1R (0.35) | NPY1RLMNAKMT2AALDH1A1PIK3C2B | |
| SCHEMBL7016178 | 0.74 | NPY1R (0.50) | NPY1R | |
| SCHEMBL7011726 | 0.73 | NPY1R (0.51) | NPY1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |