Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019783 | 0.89 | NPY1R (0.43) | NPY1RKCNH2LMNAMAPTKMT2A | |
| SCHEMBL7012960 | 0.79 | NPY1R (0.46) | NPY1RKCNH2MAPT | |
| SCHEMBL7009282 | 0.78 | PIK3CA (0.48) | NPY1RKCNH2PIK3CASIRT2SIRT1 | |
| SCHEMBL17594976 | 0.78 | PIK3CA (0.54) | PIK3CASIRT2SIRT1LMNAMAPT | |
| SCHEMBL7011726 | 0.77 | NPY1R (0.51) | NPY1RKCNH2 | |
| SCHEMBL7012855 | 0.73 | NPY1R (0.56) | NPY1RKCNH2PIK3CA | |
| SCHEMBL7012282 | 0.73 | HTR2C (0.38) | NPY1RLMNAMAPTMEN1KMT2A | |
| SCHEMBL7016178 | 0.73 | NPY1R (0.50) | NPY1R | |
| SCHEMBL7012625 | 0.73 | NPY1R (0.51) | NPY1RKCNH2 | |
| SCHEMBL7011569 | 0.73 | NPY1R (0.48) | NPY1RMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |