Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 10/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 6/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.43 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009962 | 0.89 | MEN1 (0.44) | SMN1; SMN2TP53MEN1ALDH1A1KMT2A | |
| SCHEMBL7016083 | 0.87 | HPGD (0.47) | SMN1; SMN2TP53MEN1ALDH1A1KMT2A | |
| SCHEMBL7015766 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2HRH3TP53MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7021337 | 0.86 | HRH3 (0.46) | HRH3 | |
| SCHEMBL7016154 | 0.85 | MEN1 (0.45) | SMN1; SMN2TP53MEN1ALDH1A1KMT2A | |
| SCHEMBL7014333 | 0.84 | HPGD (0.49) | SMN1; SMN2HRH3TP53MEN1ALDH1A1 | |
| SCHEMBL7011506 | 0.84 | MEN1 (0.55) | SMN1; SMN2TP53MEN1ALDH1A1KMT2A | |
| SCHEMBL7014757 | 0.84 | MEN1 (0.44) | SMN1; SMN2TP53MEN1ALDH1A1KMT2A | |
| SCHEMBL7017962 | 0.84 | LMNA (0.53) | SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL7010368 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2HRH3TP53KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |