Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447659 | 0.83 | MEN1 (0.58) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL7020129 | 0.81 | MEN1 (0.42) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| 2-Amino-4-Nitrophenol SCHEMBL6224982 | 0.77 | GAA (0.60) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL6226293 | 0.73 | MEN1 (0.46) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL5822370 | 0.71 | MEN1 (0.58) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL7299760 | 0.70 | MEN1 (0.59) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL915213 | 0.68 | MEN1 (0.64) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL655856 | 0.67 | MEN1 (0.56) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL1024222 | 0.66 | CXCR2 (0.68) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL1024223 | 0.66 | CXCR2 (0.68) | MEN1KMT2APABPC1DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358161-A2 | N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Amgen Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002055501-A2 | N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMGEN INC (US) | 2002-07-18 | — | — | WO | disclosed |