Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673054 | 0.90 | HSD17B10 (0.49) | HSD17B10LMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1530459 | 0.86 | CYP19A1 (0.44) | ALDH1A1CYP19A1TDP1 | |
| SCHEMBL5035784 | 0.83 | CYP19A1 (0.54) | LMNAALDH1A1KMT2ACYP19A1TDP1 | |
| SCHEMBL863170 | 0.83 | HSD17B10 (0.55) | HSD17B10LMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL28695929 | 0.82 | HSD17B10 (0.58) | HSD17B10LMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5913007 | 0.82 | CYP1A2 (0.51) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL3553831 | 0.82 | CYP19A1 (0.43) | ALDH1A1CYP19A1TDP1 | |
| SCHEMBL1827226 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1CYP19A1TDP1 | |
| SCHEMBL1023938 | 0.81 | MEN1 (0.41) | LMNAALDH1A1KMT2AMEN1CYP19A1 | |
| SCHEMBL5906181 | 0.79 | HTT (0.53) | LMNAALDH1A1CYP19A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |