SCHEMBL70202

SCHEMBL70202

O=C(O)c1ccccc1C=Cc1ccccc1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
ALOX15 P16050 1/20 0.62
GRIK1 P39086 1/20 0.56
GRIA1 P42261 1/20 0.56
GRIA2 P42262 1/20 0.56
GRIA3 P42263 1/20 0.56
GRIA4 P48058 1/20 0.56
GRIK2 Q13002 1/20 0.56
GRIK3 Q13003 1/20 0.56
KDM4E B2RXH2 3/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA4 P22748 3/20 0.52
HPGD P15428 2/20 0.52
CA12 O43570 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
HMGB1 P09429 1/20 0.52
CA6 P23280 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70201 1.00 ALDH1A1 (0.62) ALDH1A1ALOX15GRIK1GRIA1GRIA2
SCHEMBL8902281 1.00 ALDH1A1 (0.62) ALDH1A1ALOX15GRIK1GRIA1GRIA2
SCHEMBL1019981 0.91 GRIK1 (0.58) ALDH1A1ALOX15GRIK1GRIA1GRIA2
SCHEMBL2291774 0.91 GRIK1 (0.58) ALDH1A1ALOX15GRIK1GRIA1GRIA2
SCHEMBL13554389 0.91 GRIK1 (0.58) ALDH1A1ALOX15GRIK1GRIA1GRIA2
SCHEMBL29542528 0.91 GRIK1 (0.58) ALDH1A1ALOX15GRIK1GRIA1GRIA2
Hydrochloric Acid SCHEMBL26105180 0.89 GRIK1 (0.56) ALDH1A1ALOX15GRIK1GRIA1GRIA2
SCHEMBL1647968 0.89 CA1 (0.60) ALDH1A1ALOX15GRIK1GRIA1GRIA2
SCHEMBL10496448 0.88 HSD11B1 (0.58) ALDH1A1ALOX15GRIK1GRIA1GRIA2
SCHEMBL9797973 0.88 ALDH1A1 (0.50) ALDH1A1ALOX15GRIK1GRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-0980016-B1 ALIGNING AGENT FOR LIQUID CRYSTAL NISSAN CHEMICAL IND LTD (JP) 2008-09-24 EP disclosed
US-5521160-A COMPOUNDS FOR TREATMENT OF ATHERIOSCLEROSIS IN BLOOD VESSELS AND PREVENTION OF RESTENOSIS AFTER ANGIOPLASTY HOFFMANN-LA ROCHE INC. (US) 1996-05-28 US disclosed
US-5231223-A PROCESS FOR THE ARYLATION OF OLEFINS BAYER AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ALDH1A1 1882/4885ALOX15 1966/4885GRIK1 1056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.