Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 12/20 | 0.51 |
| ▸ | F2 | P00734 | 7/20 | 0.41 |
| ▸ | F7 | P08709 | 6/20 | 0.41 |
| ▸ | F3 | P13726 | 6/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023018 | 0.89 | TPSAB1 (0.47) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7030921 | 0.88 | TPSAB1 (0.44) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020338 | 0.84 | TPSAB1 (0.56) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7027598 | 0.73 | TPSAB1 (0.54) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7027931 | 0.73 | TPSAB1 (0.52) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7453183 | 0.73 | F7 (0.51) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7026586 | 0.72 | TPSAB1 (0.50) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7019887 | 0.71 | KMT2A (0.57) | KDM4EMEN1POLBMAPTCYP2C9 | |
| SCHEMBL7027983 | 0.67 | F2 (0.56) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7449497 | 0.67 | TPSAB1 (0.57) | TPSAB1F2F7F3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |