Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | CRHBP | P24387 | 3/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666032 | 0.86 | MAPT (0.60) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL9395569 | 0.85 | MAPT (0.72) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL27980451 | 0.79 | MAPT (0.51) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL12443496 | 0.79 | CRHBP (0.57) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL15306502 | 0.79 | MEN1 (0.56) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL27562350 | 0.77 | KMT2A (0.52) | MEN1KMT2AMAPTGAAMAPK1 | |
| SCHEMBL27805395 | 0.75 | MAPT (0.47) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL27406580 | 0.75 | LMNA (0.70) | MEN1KMT2AMAPTGAAMAPK1 | |
| SCHEMBL14871770 | 0.75 | MAPK1 (0.61) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL293916 | 0.74 | MAPT (0.72) | MEN1KMT2AMAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101694485-B | Method for utilizing affinity column to analyze holoprotein | UNIV SHANGHAI JIAOTONG | 2013-01-16 | — | — | CN | disclosed |
| CN-101694485-A | Method for utilizing affinity column to analyze holoprotein | UNIV SHANGHAI JIAOTONG | 2010-04-14 | — | — | CN | disclosed |
| EP-1280809-A1 | ANTITUMORAL ECTEINASCIDIN DERIVATIVES | PHARMA MAR, S.A. (ES) | 2003-02-05 | — | — | EP | disclosed |
| EP-1185536-A2 | HEMISYNTHETIC METHOD AND INTERMEDIATES THEREOF | PHARMA MAR, S.A. (ES) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001077115-A1 | ANTITUMORAL ECTEINASCIDIN DERIVATIVES | PHARMA MAR, S.A. (ES) | 2001-10-18 | — | — | WO | disclosed |
| WO-2000069862-A2 | HEMISYNTHETIC METHOD AND INTERMEDIATES THEREOF | PHARMA MAR, S.A. (ES) | 2000-11-23 | — | — | WO | disclosed |