SCHEMBL7020748

SCHEMBL7020748

CCCC(C)CS(=O)(=O)[N]C

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7152714 0.81
SCHEMBL11350925 0.75 TSHR (0.43) TSHR
SCHEMBL2233250 0.73 TSHR (0.42) TSHR
SCHEMBL17319467 0.73 TSHR (0.42) TSHR
SCHEMBL6729264 0.73 TSHR (0.42) TSHR
SCHEMBL1513108 0.72
SCHEMBL23805180 0.71 TSHR (0.40) TSHR
SCHEMBL5076462 0.71 TSHR (0.40) TSHR
SCHEMBL21124793 0.71 CA2 (0.40) TSHR
SCHEMBL5075666 0.71 TSHR (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003106435-A1 FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF SANKYO COMPANY, LIMITED (JP) 2003-12-24 WO disclosed