Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098613 | 0.83 | MTNR1A (0.40) | MTNR1AALDH1A1MAPTHDAC1 | |
| SCHEMBL7201899 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BCYP1A2SMN1; SMN2 | |
| SCHEMBL7198985 | 0.82 | MTNR1A (0.73) | MTNR1AMTNR1BNPSR1KMT2A | |
| SCHEMBL6075864 | 0.81 | SPR (0.41) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL7018275 | 0.78 | ERCC1 (0.45) | KDM4EALDH1A1HPGDSPRKMT2A | |
| SCHEMBL8116979 | 0.76 | CAMK2A (0.39) | MTNR1AALDH1A1NPSR1HPGDCYP3A4 | |
| SCHEMBL7205599 | 0.72 | EGFR (0.43) | KDM4EALDH1A1NPSR1MAPTHPGD | |
| SCHEMBL6077132 | 0.69 | MTNR1A (0.52) | MTNR1AMTNR1BKDM4EF13A1KMT2A | |
| SCHEMBL6077210 | 0.69 | MTNR1A (0.78) | MTNR1AMTNR1BNPSR1KMT2ADRD2 | |
| SCHEMBL8321236 | 0.68 | EGFR (0.53) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |