Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697645 | 0.92 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1GAAHTTRAB9A | |
| SCHEMBL4267215 | 0.91 | RAB9A (0.32) | SMN1; SMN2RAB9A | |
| Topramezone SCHEMBL116121 | 0.87 | — | — | |
| Topramezone SCHEMBL29566850 | 0.87 | — | — | |
| SCHEMBL6969239 | 0.85 | — | — | |
| SCHEMBL6605808 | 0.82 | HDAC9 (0.31) | — | |
| SCHEMBL13415355 | 0.82 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1GAAHTTRAB9A | |
| SCHEMBL7690468 | 0.82 | — | — | |
| SCHEMBL4702536 | 0.81 | NPC1 (0.32) | SMN1; SMN2RAB9A | |
| Topramezone SCHEMBL19838478 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11240872-A | — | — | None | — | — | JP | disclosed |
| EP-1031573-B2 | USE OF A BENZOYLPYRAZOLE COMPOUND AS HERBICIDE | NIPPON SODA CO (JP) | 2015-05-27 | — | — | EP | disclosed |
| EP-2325176-B1 | Process for the preparation of Isoxazolin-3-yl-Acylbenzenes | BASF SE (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2298749-B1 | Process for the preparation of Thioethers | BASF SE (DE) | 2014-12-24 | — | — | EP | disclosed |
| US-8124810-B2 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8049017-B2 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2011-11-01 | — | — | US | disclosed |
| US-20110152535-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | RHEINHEIMER JOACHIM | 2011-06-23 | — | — | US | disclosed |
| EP-2325176-A1 | Process for the preparation of isoxazolin-3-yl-acylbenzenes | BASF SE (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-2298749-A1 | Process for the preparation of Thioethers | BASF SE (DE) | 2011-03-23 | — | — | EP | disclosed |
| US-20100105920-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | BASF SE (DE) | 2010-04-29 | — | — | US | disclosed |
| US-6706886-B2 | HERBICIDES; 3-(2-THIO-)-PHENYLISOXAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | disclosed |
| US-6670482-B2 | Which are used as herbicides, by forming a 2-(isoxazol-3-yl)-aniline compound of given formula and then halogenation, thioalkylation, oxidation and acylation; fewer steps, efficiency | BASF AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | disclosed |
| US-20030220505-A1 | Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes | VON DEYN WOLFGANG (DE) | 2003-11-27 | — | — | US | disclosed |
| US-20030216580-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | BASF SE (DE) | 2003-11-20 | — | — | US | disclosed |
| US-20030028033-A1 | Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes | DEYN WOLFGANG VON (DE) | 2003-02-06 | — | — | US | disclosed |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2003-01-23 | — | — | US | disclosed |
| US-6469176-B1 | CROP PROTECTION COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| US-6147031-A | Benzoylpyrazole compounds, intermediate preparing therefor and herbicides | NIPPON SODA CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-1031573-A1 | NOVEL BENZOYLPYRAZOLE COMPOUNDS, INTERMEDIATES, AND HERBICIDES | NIPPON SODA CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| JP-H11240872-A | NEW BENZOYLPYRAZOLE COMPOUND, INTERMEDIATE FOR ITS PRODUCTION AND HERBICIDE | NIPPON SODA CO LTD | 1999-09-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152535-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | CBR3, CYP4X1, UQCRB | SMN1; SMN2 4343/4885ALDH1A1 549/4885GAA 3978/4885 |
| US-20100105920-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | CBR3, CYP4X1, UQCRB | SMN1; SMN2 4343/4885ALDH1A1 549/4885GAA 3978/4885 |
| US-20030220505-A1 | Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes | CYP2F1, CBR3, CBR1 | SMN1; SMN2 4698/4885ALDH1A1 229/4885GAA 4212/4885 |
| US-20030216580-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | UQCRB, CYP1B1, CYP2F1 | SMN1; SMN2 4162/4885ALDH1A1 274/4885GAA 4064/4885 |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | CYP2F1, UQCRB, CYP1B1 | SMN1; SMN2 4220/4885ALDH1A1 352/4885GAA 4157/4885 |
| US-20030028033-A1 | Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes | CYP2F1, CBR3, CBR1 | SMN1; SMN2 4698/4885ALDH1A1 229/4885GAA 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.