Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 9/20 | 1.00 |
| ▸ | CA1 | P00915 | 3/20 | 0.77 |
| ▸ | CA2 | P00918 | 3/20 | 0.77 |
| ▸ | ACHE | P22303 | 3/20 | 0.77 |
| ▸ | DRD2 | P14416 | 4/20 | 0.68 |
| ▸ | DRD4 | P21917 | 3/20 | 0.68 |
| ▸ | DRD3 | P35462 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731034 | 1.00 | MTNR1A (1.00) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL11960204 | 1.00 | MTNR1A (1.00) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL3919777 | 0.90 | MTNR1A (1.00) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL14452758 | 0.88 | MTNR1A (0.79) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL2351965 | 0.86 | MTNR1A (0.84) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL2597485 | 0.86 | MTNR1A (0.84) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL30089783 | 0.86 | MTNR1A (0.84) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL10464119 | 0.85 | MTNR1A (0.74) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL11496541 | 0.83 | MTNR1A (0.72) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL6513612 | 0.83 | MTNR1A (0.70) | MTNR1AMTNR1BCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278885-A1 | RESOLUTION OF AMINOTETRALINS | TORCAN CHEMICAL Ltd (CA) | 2003-01-29 | — | — | EP | claimed |
| WO-2001083807-A1 | RESOLUTION OF AMINOTETRALINS | TORCAN CHEMICAL LTD. (CA) | 2001-11-08 | — | — | WO | claimed |