Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.84 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.84 |
| ▸ | MAPT | P10636 | 1/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.84 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.84 |
| ▸ | CA1 | P00915 | 2/20 | 0.72 |
| ▸ | CA2 | P00918 | 2/20 | 0.72 |
| ▸ | ACHE | P22303 | 2/20 | 0.72 |
| ▸ | DRD2 | P14416 | 6/20 | 0.67 |
| ▸ | DRD4 | P21917 | 5/20 | 0.67 |
| ▸ | DRD3 | P35462 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089783 | 1.00 | MTNR1A (0.84) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL2351965 | 1.00 | MTNR1A (0.84) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL55299 | 0.91 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL17335643 | 0.88 | MTNR1A (0.81) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7021164 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL11960204 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL9731034 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL14452758 | 0.85 | MTNR1A (0.79) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7332063 | 0.84 | MTNR1A (0.63) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7333054 | 0.84 | MTNR1A (0.63) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234057-B | Preparation method of rotigotine | 成都工业学院 | 2022-12-02 | — | — | CN | disclosed |
| CN-113234057-A | Preparation method of rotigotine | 成都工业学院 | 2021-08-10 | — | — | CN | disclosed |
| EP-2531486-B1 | NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2017-06-21 | — | — | EP | disclosed |
| US-8729306-B2 | Process for the preparation of nitrogen substituted aminotetralins derivatives | UCB PHARMA GMBH (DE) | 2014-05-20 | — | — | US | disclosed |
| US-8729306-B2 | Process for the preparation of nitrogen substituted aminotetralins derivatives | UCB PHARMA GMBH (DE) | 2014-05-20 | — | — | US | disclosed |
| US-20120302790-A1 | Novel Process for the Preparation of Nitrogen Substituted Aminotetralins Derivatives | UCB PHARMA, S.A. (BE) | 2012-11-29 | — | — | US | disclosed |
| US-20120302790-A1 | Novel Process for the Preparation of Nitrogen Substituted Aminotetralins Derivatives | UCB PHARMA, S.A. (BE) | 2012-11-29 | — | — | US | disclosed |
| WO-2011146610-A2 | AN ENANTIOSELECTIVE SYNTHESIS OF CHIRAL AMINES FOR THE PRODUCTION OF ROTIGOTINE | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011095539-A2 | NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES | UCB PHARMA GMBH (DE) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302790-A1 | Novel Process for the Preparation of Nitrogen Substituted Aminotetralins Derivatives | AADAT, AANAT, ASNS | MTNR1A 1238/4885MTNR1B 913/4885CYP1A2 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.