Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.64 |
| ▸ | F10 | P00742 | 1/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | PLAT | P00750 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487625 | 1.00 | F2 (0.64) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7027350 | 0.93 | F2 (0.62) | F2F10PLGPLATPRSS1 | |
| SCHEMBL8491944 | 0.93 | F2 (0.62) | F2F10PLGPLATPRSS1 | |
| SCHEMBL8489097 | 0.92 | F2 (0.60) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7026062 | 0.92 | F2 (0.60) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7023605 | 0.90 | F2 (0.60) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7017279 | 0.90 | F2 (0.79) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7017283 | 0.90 | F2 (0.79) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7015978 | 0.89 | F2 (0.78) | F2F10PLGPLATPRSS1 | |
| SCHEMBL8488500 | 0.89 | F2 (0.78) | F2F10PLGPLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739886-B1 | Selective thrombin inhibitors | LG CHEMICAL LTD (KR) | 2003-10-01 | — | — | EP | disclosed |
| US-5985899-A | ANTICOAGULANTS | LG CHEMICAL LTD. (KR) | 1999-11-16 | — | — | US | disclosed |
| US-5977114-A | Selective thrombin inhibitors | LG CHEMICAL LTD. (KR) | 1999-11-02 | — | — | US | disclosed |
| EP-0739886-A2 | Selective thrombin inhibitors | LG Chemical Limited (KR) | 1996-10-30 | — | — | EP | disclosed |