SCHEMBL702177

SCHEMBL702177

COc1cccc([SiH3])c1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.56
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
NFE2L2 Q16236 5/20 0.44
MAPK1 P28482 2/20 0.44
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL151213 0.82 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL25434306 0.82 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL27753904 0.82 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
Ammonia Solution, Strong SCHEMBL4268652 0.79 SMN1; SMN2 (0.58) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL27731704 0.79 SMN1; SMN2 (0.58) SMN1; SMN2CA12CA1CA2CA4
Hydrochloric Acid SCHEMBL31658961 0.79 SMN1; SMN2 (0.58) SMN1; SMN2CA12CA1CA2CA4
Bromide SCHEMBL28158222 0.79 SMN1; SMN2 (0.58) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL308029 0.78 MAPT (0.43) SMN1; SMN2CA12CA1CA2CA4
Bromide SCHEMBL1307432 0.77 SMN1; SMN2 (0.56) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL8375522 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751880-A Modified fluorosilicone polymer, two-component silicone sealant and preparation method thereof 广州白云科技股份有限公司 2025-04-04 CN claimed
CN-119751877-A Modified fluorosilicone cross-linking agent, double-component silicone sealant and preparation method thereof 广州白云科技股份有限公司 2025-04-04 CN claimed
EP-1225194-B2 Method of forming a dielectric interlayer film with organosilicon precursors AIR PROD & CHEM (US) 2013-09-18 EP claimed
EP-1225194-B1 Method of forming a dielectric interlayer film with organosilicon precursors AIR PROD & CHEM (US) 2008-10-01 EP claimed
US-6583048-B2 Chemical vapor deposition from a silyl ether, a silyl ether oligomer, or an organosilicon compound containing one or more reactive groups, to form an interlayer dielectric film having a dielectric constant of 3.5 or less. AIR PRODUCTS AND CHEMICALS, INC. 2003-06-24 US claimed
US-20020142579-A1 ORGANOSILICON PRECURSORS FOR INTERLAYER DIELECTRIC FILMS WITH LOW DIELECTRIC CONSTANTS VERSUM MATERIALS US, LLC 2002-10-03 US claimed
EP-1225194-A2 Method of forming a dielectric interlayer film with organosilicon precursors AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-07-24 EP claimed
US-20260128377-A1 ELECTROLYTE WITH HIGH LIFSI CONCENTRATION ARKEMA FRANCE (FR) 2026-05-07 US disclosed
EP-4716967-A1 ELECTROLYTE WITH HIGH LIFSI CONCENTRATION ARKEMA France (FR) 2026-04-01 EP disclosed
EP-4703405-A1 CRYSTALLINE POLYOXYALKYLENE-BASED POLYMER AND CURABLE COMPOSITION COMPRISING SAME Kaneka Corporation (JP) 2026-03-04 EP disclosed
EP-3950832-B1 CURABLE COMPOSITION AND CURED PRODUCT KANEKA CORP (JP) 2025-10-22 EP disclosed
EP-3889206-B1 POLYOXYALKYLENE POLYMER AND CURABLE COMPOSITION KANEKA CORP (JP) 2025-10-15 EP disclosed
EP-4596622-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2025-08-06 EP disclosed
EP-1195397-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR Corporation (JP) 2002-04-10 EP disclosed
US-6303728-B1 REACTING SILICON HYDRIDE COMPOUND, E.G., DICHLOROMETHYLSILANE WITH AN ALKENYL GROUP-CONTAINING COMPOUND, E.G., ALLYL-TERMINATED POLYISOBUTYLENE; CATALYST OF A GROUP VIII METAL-CONTAINING CATALYST AND A SULFUR COMPOUND KANEKA CORPORATION (JP) 2001-10-16 US disclosed
US-6121379-A Processes for producing polymers having functional groups KANEKA CORPORATION (JP) 2000-09-19 US disclosed
EP-1000951-A1 HYDROSILYLATION PROCESS AND POLYMERS PRODUCED BY THE PROCESS KANEKA CORPORATION (JP) 2000-05-17 EP disclosed
US-5998509-A BLEND OF AN EPOXY RESIN, POLYSILOXANE CURING AGENT AND FILLER KABUSHIKI KAISHA TOSHIBA (JP) 1999-12-07 US disclosed
EP-0864588-A1 PROCESSES FOR PRODUCING POLYMERS HAVING FUNCTIONAL GROUPS KANEKA CORPORATION (JP) 1998-09-16 EP disclosed
EP-0212063-B1 URETHANE RESINS CONTAINING HYDROLYZABLE MOIETIES FROM ORGANOSILANE COMPOUNDS PPG INDUSTRIES, INC. (US) 1990-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260128377-A1 ELECTROLYTE WITH HIGH LIFSI CONCENTRATION CCNI, FLI1, FOS SMN1; SMN2 1085/4885CA12 507/4885CA1 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.