Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.77 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813950 | 0.95 | MTNR1A (0.71) | MTNR1ATRPV1MTNR1BFAAHPTGS2 | |
| SCHEMBL6077096 | 0.94 | MTNR1A (0.67) | MTNR1ATRPV1MTNR1BFAAHPTGS2 | |
| SCHEMBL7016887 | 0.87 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL8884045 | 0.87 | MTNR1A (1.00) | MTNR1ATRPV1MTNR1B | |
| SCHEMBL7017936 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL27540716 | 0.83 | MTNR1A (0.57) | MTNR1AMTNR1B | |
| SCHEMBL5347056 | 0.82 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL27449304 | 0.82 | MTNR1A (0.67) | MTNR1AMTNR1B | |
| SCHEMBL7024425 | 0.81 | MTNR1A (0.66) | MTNR1AMTNR1B | |
| SCHEMBL6075680 | 0.81 | MTNR1A (0.66) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1128142-C | Novel substituted dipolymer compounds, prepn. method therefor, pharmaceutical compositions contg. same | ADIR (FR) | 2003-11-19 | — | — | CN | disclosed |
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| CN-1277962-A | Novel substituted dipolymer compounds, prepn. method therefor, pharmaceutical compositions contg. same | ADIR (FR) | 2000-12-27 | — | — | CN | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |