Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8881811 | 0.94 | MTNR1A (0.89) | MTNR1AMTNR1B | |
| SCHEMBL8883537 | 0.88 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7022006 | 0.87 | MTNR1A (0.77) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL7016887 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BHSD17B10 | |
| SCHEMBL7017936 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BHSD17B10 | |
| SCHEMBL1924859 | 0.84 | MTNR1A (0.79) | MTNR1AMTNR1BHSD17B10MAPT | |
| SCHEMBL3813950 | 0.83 | MTNR1A (0.71) | MTNR1AMTNR1BHSD17B10TRPV1MEN1 | |
| SCHEMBL8883384 | 0.82 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL27449304 | 0.81 | MTNR1A (0.67) | MTNR1AMTNR1BHSD17B10 | |
| SCHEMBL6077096 | 0.81 | MTNR1A (0.67) | MTNR1AMTNR1BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693665-A | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-02 | — | — | US | claimed |