Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.75 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.63 |
| ▸ | HTR2C | P28335 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SPR | P35270 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1270126 | 0.83 | NPSR1 (0.68) | MPOTRPV1KDM4EALDH1A1NPSR1 | |
| SCHEMBL20182374 | 0.83 | NPSR1 (0.68) | MPOTRPV1KDM4EALDH1A1NPSR1 | |
| SCHEMBL19399613 | 0.82 | ALDH1A1 (0.74) | MPOKDM4EALDH1A1LMNATDP1 | |
| SCHEMBL13996187 | 0.82 | SPR (0.73) | TRPV1KDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL7002494 | 0.81 | HTR2C (0.77) | KDM4EALDH1A1NPSR1LMNATDP1 | |
| SCHEMBL25884522 | 0.81 | NPSR1 (0.64) | MPOTRPV1KDM4EALDH1A1NPSR1 | |
| SCHEMBL31036202 | 0.80 | TRPV1 (0.91) | TRPV1KDM4EALDH1A1NPSR1CYP2D6 | |
| SCHEMBL27959048 | 0.80 | TRPV1 (0.59) | MPOTRPV1KDM4EALDH1A1NPSR1 | |
| SCHEMBL6220357 | 0.80 | CYP2D6 (0.71) | TRPV1KDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL7100086 | 0.79 | SPR (0.76) | TRPV1KDM4EALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |