Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CDC25B | P30305 | 4/20 | 0.61 |
| ▸ | CDC25A | P30304 | 1/20 | 0.57 |
| ▸ | CDC25C | P30307 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69303 | 0.95 | TSHR (0.63) | TSHRCDC25BCDC25ACDC25CALDH1A1 | |
| SCHEMBL11338215 | 0.88 | TSHR (0.63) | TSHRCDC25BCDC25ACDC25CALDH1A1 | |
| SCHEMBL17614211 | 0.88 | CDC25B (0.56) | TSHRCDC25BCDC25ACDC25CALDH1A1 | |
| SCHEMBL29113041 | 0.88 | ALDH1A1 (0.65) | TSHRCDC25BCDC25ACDC25CALDH1A1 | |
| SCHEMBL1164310 | 0.85 | TSHR (0.67) | TSHRALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL277672 | 0.85 | CDC25B (0.82) | TSHRCDC25BCDC25ACDC25CALDH1A1 | |
| Diethyl Phthalate SCHEMBL28305370 | 0.85 | TSHR (0.75) | TSHRCDC25BCDC25ACDC25CALDH1A1 | |
| SCHEMBL2492898 | 0.84 | TSHR (0.68) | TSHRALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL10488875 | 0.84 | CDC25B (0.58) | TSHRCDC25BCDC25ACDC25CALDH1A1 | |
| SCHEMBL162383 | 0.83 | TSHR (0.53) | TSHRCDC25BCDC25ACDC25CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003532733-A | — | — | 2003-11-05 | — | — | JP | claimed |
| EP-1282625-A1 | BENZOXAZINES FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | WARNER-LAMBERT COMPANY (US) | 2003-02-12 | — | — | EP | claimed |
| WO-2001085734-A1 | BENZOXAZINES FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | WARNER-LAMBERT COMPANY (US) | 2001-11-15 | — | — | WO | claimed |
| EP-4010441-B1 | LOW DIELECTRIC CONSTANT SILICEOUS FILM MANUFACTURING COMPOSITION AND METHODS FOR PRODUCING CURED FILM AND ELECTRONIC DEVICE USING THE SAME | MERCK PATENT GMBH (DE) | 2023-09-06 | — | — | EP | disclosed |
| US-11512171-B2 | Low dielectric constant siliceous film manufacturing composition and methods for producing cured film and electronic device using the same | MERCK PATENT GMBH (DE) | 2022-11-29 | — | — | US | disclosed |
| US-20220267532-A1 | LOW DIELECTRIC CONSTANT SILICEOUS FILM MANUFACTURING COMPOSITION AND METHODS FOR PRODUCING CURED FILM AND ELECTRONIC DEVICE USING THE SAME | MERCK PATENT GMBH (DE) | 2022-08-25 | — | — | US | disclosed |
| EP-4010441-A1 | LOW DIELECTRIC CONSTANT SILICEOUS FILM MANUFACTURING COMPOSITION AND METHODS FOR PRODUCING CURED FILM AND ELECTRONIC DEVICE USING THE SAME | Merck Patent GmbH (DE) | 2022-06-15 | — | — | EP | disclosed |
| CN-114207043-A | Composition for producing low dielectric constant siliceous film and method for producing cured film and electronic device using the same | 默克专利有限公司 | 2022-03-18 | — | — | CN | disclosed |
| WO-2021028297-A1 | LOW DIELECTRIC CONSTANT SILICEOUS FILM MANUFACTURING COMPOSITION AND METHODS FOR PRODUCING CURED FILM AND ELECTRONIC DEVICE USING THE SAME | MERCK PATENT GMBH (DE) | 2021-02-18 | — | — | WO | disclosed |
| US-7399782-B2 | Polyether brevetoxin derivatives as a treatment for cystic fibrosis, mucociliary dysfunction, and pulmonary diseases | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2008-07-15 | — | — | US | disclosed |
| EP-1282625-A1 | BENZOXAZINES FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | WARNER-LAMBERT COMPANY (US) | 2003-02-12 | — | — | EP | disclosed |
| CN-1344270-A | Functionalized heterocycles as chemokine receptor modulators | THOUSAND YEARS MEDICAMENTS INC (US) | 2002-04-10 | — | — | CN | disclosed |
| WO-2001085734-A1 | BENZOXAZINES FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | WARNER-LAMBERT COMPANY (US) | 2001-11-15 | — | — | WO | disclosed |
| EP-0579510-A2 | Propylene polymers and process for preparing the same | Mitsubishi Chemical Corporation (JP) | 1994-01-19 | — | — | EP | disclosed |