Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.39 |
| ▸ | RXRA | P19793 | 5/20 | 0.39 |
| ▸ | RARA | P10276 | 5/20 | 0.39 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | FSHR | P23945 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224084 | 1.00 | RARB (0.39) | RARBRXRARARARXRBRXRG | |
| SCHEMBL6221173 | 0.91 | RXRA (0.39) | RARBRXRARARARXRBRXRG | |
| SCHEMBL7023001 | 0.85 | KDM1A (0.47) | RARBRXRARARARXRBRXRG | |
| SCHEMBL6224587 | 0.85 | KDM1A (0.47) | RARBRXRARARARXRBRXRG | |
| SCHEMBL7025785 | 0.85 | KDM1A (0.47) | RARBRXRARARARXRBRXRG | |
| SCHEMBL6222075 | 0.81 | RXRA (0.46) | RARBRXRARARARXRBRXRG | |
| SCHEMBL8606352 | 0.77 | RXRA (0.48) | RARBRXRARARARXRBRXRG | |
| SCHEMBL21017967 | 0.77 | RXRA (0.48) | RARBRXRARARARXRBRXRG | |
| SCHEMBL8332983 | 0.77 | RXRA (0.48) | RARBRXRARARARXRBRXRG | |
| SCHEMBL8332791 | 0.77 | RXRA (0.48) | RARBRXRARARARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354878-A2 | Tetrahydroquinoline derivatives having selective activity for retinoid x receptors | Allergan, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |