Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720423 | 0.93 | ELANE (0.39) | ELANEATMKDM1AHDAC3HDAC4 | |
| SCHEMBL7458631 | 0.93 | ELANE (0.39) | ELANEATMKDM1AHDAC3HDAC4 | |
| SCHEMBL7017071 | 0.84 | SMN1; SMN2 (0.40) | ATMKDM4EGAAMAPTHPGD | |
| SCHEMBL7016941 | 0.82 | ATM (0.46) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7018122 | 0.82 | ATM (0.46) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8717966 | 0.78 | SCN9A (0.49) | SCN9APTPN1ITGB3ITGA2BMMP13 | |
| SCHEMBL8717972 | 0.78 | SCN9A (0.49) | SCN9APTPN1ITGB3ITGA2BMMP13 | |
| SCHEMBL7465905 | 0.78 | ATM (0.51) | ELANEATMKDM1AHDAC8PCNA | |
| SCHEMBL7465898 | 0.78 | ATM (0.51) | ELANEATMKDM1AHDAC8PCNA | |
| SCHEMBL7452715 | 0.76 | CTSS (0.41) | ATMHPGDSCN9APTPN1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149076-B1 | O-THIOCARBAMOYL-AMINOALKANOL COMPOUNDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR PREPARING THE SAME | SK CORP (KR) | 2003-10-22 | — | — | EP | disclosed |
| EP-1149076-A1 | O-THIOCARBAMOYL-AMINOALKANOL COMPOUNDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR PREPARING THE SAME | SK Corporation (KR) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000046191-A1 | O-THIOCARBAMOYL-AMINOALKANOL COMPOUNDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR PREPARING THE SAME | SK CORPORATION (KR) | 2000-08-10 | — | — | WO | disclosed |