Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717966 | 1.00 | SCN9A (0.49) | SCN9AITGB3ITGA2BACEPTPN1 | |
| SCHEMBL7458631 | 0.85 | ELANE (0.39) | SCN9AITGB3ITGA2BPTPN1MMP13 | |
| SCHEMBL8720423 | 0.85 | ELANE (0.39) | SCN9AITGB3ITGA2BPTPN1MMP13 | |
| SCHEMBL31407522 | 0.82 | ACE (0.55) | SCN9AITGB3ITGA2BACEPTPN1 | |
| SCHEMBL31407438 | 0.82 | ACE (0.55) | SCN9AITGB3ITGA2BACEPTPN1 | |
| SCHEMBL14343235 | 0.80 | ITGB3 (0.65) | ITGB3ITGA2BACEPTPN1ITGB1 | |
| SCHEMBL16909032 | 0.80 | ITGB3 (0.65) | ITGB3ITGA2BACEPTPN1ITGB1 | |
| SCHEMBL1087185 | 0.80 | ITGB3 (0.65) | ITGB3ITGA2BACEPTPN1ITGB1 | |
| SCHEMBL19554118 | 0.80 | ACE (0.47) | SCN9AITGB3ITGA2BACEPTPN1 | |
| SCHEMBL5107823 | 0.79 | SCN9A (0.65) | SCN9AACECTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756817-A | TREATMENT OF DISEASES OF CENTRAL NERVOUS SYSTEMS | YUKONG LIMITED (KR) | 1998-05-26 | — | — | US | disclosed |