⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217072 | 0.85 | — | — | |
| SCHEMBL17229157 | 0.85 | MEN1 (1.00) | — | |
| SCHEMBL10101148 | 0.85 | MEN1 (0.89) | — | |
| SCHEMBL9259257 | 0.82 | MEN1 (0.94) | — | |
| SCHEMBL21765846 | 0.82 | MEN1 (0.94) | — | |
| SCHEMBL11758762 | 0.82 | MEN1 (0.94) | — | |
| SCHEMBL277343 | 0.80 | — | — | |
| SCHEMBL12799428 | 0.79 | MEN1 (0.78) | — | |
| SCHEMBL718284 | 0.78 | MEN1 (0.85) | — | |
| SCHEMBL311295 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064253-B1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 2003-01-29 | — | — | EP | claimed |
| US-6346633-B1 | TERT-AMINOPHENYLESTER OF ACID | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | claimed |
| EP-1064253-A1 | ANTI-TUMOUR AGENTS | AstraZeneca AB (SE) | 2001-01-03 | — | — | EP | claimed |
| WO-1999048857-A1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 1999-09-30 | — | — | WO | claimed |
| EP-1064253-B1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 2003-01-29 | — | — | EP | disclosed |
| US-6346633-B1 | TERT-AMINOPHENYLESTER OF ACID | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | disclosed |
| EP-1064253-A1 | ANTI-TUMOUR AGENTS | AstraZeneca AB (SE) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999048857-A1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 1999-09-30 | — | — | WO | disclosed |
| US-5618814-A | Trisubstituted pyrimido [5,4-d] pyrimidines for modulating multi-drug resistance and pharmaceutical compositions containing these compounds | DR. KARL THOMAE GMBH (DE) | 1997-04-08 | — | — | US | disclosed |